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Exercise fuels the brain's stress buffers

Exercise may improve mental health by helping the brain cope better with stress, according to research into the effect of exercise on neurochemicals involved in the body's stress response.

Preliminary evidence suggests that physically active people have lower rates of anxiety and depression than sedentary people. But little work has focused on why that should be. So to determine how exercise might bring about its mental health benefits, some researchers are looking at possible links between exercise and brain chemicals associated with stress, anxiety, and depression.

So far there's little evidence for the popular theory that exercise causes a rush of endorphins. Rather, one line of research points to the less familiar neuromodulator norepinephrine, which may help the brain deal with stress more efficiently.

Work in animals since the late 1980s has found that exercise increases brain concentrations of norepinephrine in brain regions involved in the body's stress response.

Norepinephrine is particularly interesting to researchers because 50 percent of the brain's supply is produced in the locus coeruleus, a brain area that connects most of the brain regions involved in emotional and stress responses. The chemical is thought to play a major role in modulating the action of other, more prevalent neurotransmitters that play a direct role in the stress response. And although researchers are unsure of exactly how most antidepressants work, they know that some increase brain concentrations of norepinephrine.

But some psychologists don't think it's a simple matter of more norepinephrine equals less stress and anxiety and therefore less depression. Instead, they think exercise thwarts depression and anxiety by enhancing the body's ability to respond to stress.

Biologically, exercise seems to give the body a chance to practice dealing with stress. It forces the body's physiological systems - all of which are involved in the stress response - to communicate much more closely than usual: The cardiovascular system communicates with the renal system, which communicates with the muscular system. And all of these are controlled by the central and sympathetic nervous systems, which also must communicate with each other. This workout of the body's communication system may be the true value of exercise; the more sedentary we get, the less efficient our bodies in responding to stress.


Zzzzzzzzz... I can't sleep

Why is sleep important to my mental health?

Another sleepless night. You toss and turn, trying to banish worries about your family, job, money. As you fret about how miserable and inefficient you'll be tomorrow, you become even more tense. Sometimes, even with your mind seemingly clear and relaxed, sleep just doesn't come.

An estimated 40 percent of adults in the United States suffer from sleep disturbances each year, and 60% of those report having insomnia a few nights a week or more.

Insomnia includes having trouble falling asleep, having trouble getting back to sleep, and waking up too early. It's more common in people with a history of depression and bipolar disorder.

Sleep maintains your circadian rhythms, the 24-hour cycle that regulates your physical and mental functions. A good night's sleep helps the brain commit information to memory. Many adults function best with around eight hours of sleep, but each person has unique needs.

Our brain makes mood-enhancing hormones while we're sleeping, and if we get too little sleep, it won't make and store enough for the next day. A lack of sleep leads to poor concentration, irritability, anxiety, depression and low energy. And, chronic sleep deprivation can cause weight gain by affecting the way our bodies process and store carbohydrates and by altering levels of hormones that affect our appetite.

More than 80 percent of individuals who suffer from depression also have sleep abnormalities, and if sleep problems persist after depression has subsided, the risk of relapse and even suicide increases. Research has found, and many of us know from experience, that sleep problems can lead to depression, and depression can lead to sleep problems. Lack of sleep can also trigger mania or hypomania in people with bipolar disorder. A regular sleep-wake schedule can help prevent occurrences.

What causes insomnia?

In addition to depression symptoms, stressful events can cause insomnia and so does eating too close to bedtime. Alcohol can cause you to fall asleep but cause a rebound effect two or three hours later and keep you awake. Some medications can cause sleep disturbances, including many of those for mood disorders.


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