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Bipolar II and bipolar spectrum disorder
Table 1. Bipolarity: clues in the history

  

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Recurrent major depressive episodes (> 3)

  1. Early age of onset of major depressive episode (< age 25)
  2. Family history of bipolar disorder in first-degree relative
  3. Hyperthymic [over-active] personality (at baseline, nondepressed state)
  4. Atypical depressive symptoms (DSM-IV criteria)
  5. Brief major depressive episodes (on average, < 3 months)
  6. Psychotic major depressive episodes
  7. Postpartum depression
  8. Antidepressant-induced mania or hypomania
  9. Antidepressant "wear-off" (acute but not prophylactic response)
  10. Lack of response to 3 adequate antidepressant treatment trials

 

  

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Page updated March 1, 2011